Boon said that while characters like Cassie Cage will not rule out the inclusion of related classic character like her parents, Johnny Cage and Sonya Blade, the focus is on bringing new players to the forefront. He even said that NetherRealm Studios is "probably introducing more [new characters] in this game than in any other MK title ever." Boon was quick, however, to say that old favorites could always be added to the game later by way of DLC.
Boon also talked more about MKX's story and the time jumps that will occur throughout. He claimed that gamers will see big shifts in power over the course of the narrative, and that flashbacks and jumps forward of 5 to 10 years will be used. Boon even admitted that once the story of MKX is complete he's not sure where Mortal Kombat will go from there.
The whole interview can be found at IGN.